Persistent Fatigue and Weakness:
Chronic fatigue and weakness are common but often overlooked symptoms of kidney disease. As kidneys struggle to effectively filter waste and toxins from the bloodstream, the accumulation of metabolic byproducts can lead to systemic fatigue and lethargy. Furthermore, anemia, a condition characterized by low red blood cell count, commonly accompanies kidney disease, exacerbating feelings of tiredness and weakness. Individuals experiencing unexplained or persistent fatigue should consider kidney function evaluation as part of their diagnostic workup.

Swelling (Edema) in Extremities:
Edema, or swelling, in the legs, ankles, feet, or hands is a classic manifestation of kidney disease. When kidneys fail to adequately remove excess fluid from the body, fluid retention occurs, leading to swelling in the extremities. This swelling may be particularly noticeable in the morning or after prolonged periods of sitting or standing. Edema accompanied by other symptoms such as shortness of breath or high blood pressure warrants immediate medical attention, as it may indicate advanced kidney dysfunction.

Elevated Blood Pressure:
High blood pressure (hypertension) is both a cause and a consequence of kidney disease. Dysfunction in the kidneys’ ability to regulate blood pressure can lead to hypertension, which, in turn, exacerbates kidney damage. Individuals with uncontrolled or resistant hypertension should undergo thorough kidney function assessment to identify underlying renal pathology. Conversely, persistent elevation of blood pressure despite lifestyle modifications and antihypertensive medications may signal renal involvement, necessitating further investigation.